As the Fantastic Four embark on a strange mission, they aren't at beginnings, but an end! Marvel's first family heads towards their darkest hour, who is behind their downfall? Manhattan is under attack from a corrupted universe, to defeat it; the Human Torch must make a terrible sacrifice! With one member down, a new menace emerges: the Wrecking Crew, their powers elevated! As Ben and Alicia's romance rekindles, threats of Fin Fang Foom, the Wizard and Puppet Master Loom, the Baxter Building quarantined, and the Fantastic Four are held accountable!